Cancer biology II
Summary
The course covers in detail the interactions of cancer cells with their environment with an emphasis on tumor-angiogenesis, inflammation, adaptive and innate immunity and cancer-induced immune suppression. Additional topics are cancer metabolism, cancer stem cells and metastasis.
Content
The 2x5 credit course Cancer Biology I+II starts in the winter semester and continues throughout the summer semester.
Cancer Biology II covers:
- complex oncogenic signaling networks and hierarchical tumor organization
- tumor metabolism
- cell death signaling and apoptosis
- cancer histology with pratical training
- inflammatory signaling in cancer
- tumor angiogenesis
- tumor cell dissemination and metastasis
- innate immunity: pro-tumorigenic roles of inflammation, NK cells
- adaptive immunity: immuno editing, immune evasion, immunotherapy
Two weeks on tumor angiogenesis will be given by Prof. de Palma, all other weeks and topics will be given by Prof. Huelsken.
The weekly lectures will be followed by exercises. The task for these exercises will be student presentations of scientific articles which illustrate the course in order to consolidate the knowledge of the course topics.
Learning Prerequisites
Recommended courses
Cancer Biolgy I
Immunology
Assessment methods
Continuous evaluation during the semester with two intermediate exams
Resources
Bibliography
The Biology of Cancer, Robert A. Weinberg
Ressources en bibliothèque
Moodle Link
Dans les plans d'études
- Semestre: Printemps
- Forme de l'examen: Pendant le semestre (session d'été)
- Matière examinée: Cancer biology II
- Cours: 3 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Type: optionnel
- Semestre: Printemps
- Forme de l'examen: Pendant le semestre (session d'été)
- Matière examinée: Cancer biology II
- Cours: 3 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Type: optionnel