Bio-nano-chip design
Summary
Introduction to heterogeneous integration for Nano-Bio-CMOS sensors on Chip. Understanding and designing of active Bio/CMOS interfaces powered by nanostructures.
Content
Currents and capacitive-effects in water solutions
Introduction to biological molecules
Thermodynamics of molecular Interactions
Nanotechnology for molecular assembly on chip surfaces
Nanotechnology to prevent electron transfer
Nanotechnology to enhance electron transfer
Chip design for electrochemical sensing: basic configurations
Chip design for biosensing with label-free capacitance mode (CBCM & FTCM Methods)
Chip design for biosensing in constant-bias (Current-to-Voltage & FTCC Methods)
Chip design for biosensing in voltage-scan (VDCM & DDSM Methods)
Keywords
OpAmp, CMOS, biosensors, carbon nanotubes, alkane/silane thiols, proteins, DNA
Learning Prerequisites
Recommended courses
Electronics I (BS course)
General chemistry OR Chemistry of surfaces (both BS courses)
Analysis IV (BS course)
Learning Outcomes
By the end of the course, the student must be able to:
- Choose bio materials
- Choose nano materials
- Judge an electrical interface
- Design complex analog circuits for electrochemical biosensing
- Design Bio-Nano-CMOS-sensing devices at system level
- Realize and discuss nanotechnology and molecular layers on chip Investigate
- Discuss biotechnology to Realize biosensors on chip
Teaching methods
Ex cathedra, exercises, and group-project with the help of Teaching Assistants
Expected student activities
Following the ex-cathedra lectures, active participation to the Q/A sessions organize during the ex-cathedra lectures, home work on lectures' slides as well as on the proposed excercies, work in class as well as at home on the group project.
Assessment methods
Written exam and group-project report
Resources
Bibliography
- Course slides
- Book: S.Carrara, Bio/CMOS Interfaces and Co-Design, Springer, NY, 2013
- Book: S.Carrara, Bio/CMOS Interfaces and Co-Design, 2nd edition, Springer, NY, 2024
Ressources en bibliothèque
Notes/Handbook
https://link.springer.com/book/10.1007/978-1-4614-4690-3 (1st Edition, 2013)
https://link.springer.com/book/10.1007/978-3-031-31832-0 (2nd Edition, 2024, 4 more chapters, and 5 more appendixes)
Websites
Moodle Link
In the programs
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: Written (winter session)
- Subject examined: Bio-nano-chip design
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional