Translational neuroengineering

The students will be introduced in the physiology and pathophysiology of core neurological disorders, such as e.g., stroke, spinal cord injury or neurodegenerative disorders, followed by aspects of respective clinical translational, technological development and neuroengineering in these clinical domains and important regulatory, neuroethical and R&D points. The course content is organized as follows. Each week 2 x 1.5 h lectures and 3h exercise.

Lecture topics:

Memory-Learning: Physiology (FH)

Dementia: Background/Pathophysiology (FH)

Motor cortical functioning: Physiology (FH)

Stroke: Background/Pathophysiology (FH)

Cognitive Functioning (Attention, frontal-executive, language): Physiology (FH)

Traumatic Brain Injury, Stroke: Background/Pathophysiology (FH)

Technology- Non-invasive brain stimulation (NIBS): Introduction in Methods and Concepts (FH)

Technology-Translation Stroke, TBI: NIBS technology (TMS, tES, TI) in stroke and dementia (FH)

Visual, auditory functioning: Physiology (SM/FH)

Pre-, postchiasmatic visual deficits (e.g., retinitis pigmentosa, congenital deafness): Background/Pathophysiology (SM/FH)

Technology- Perceptual prosthetics: Introduction in Methods and Concepts (SM)

Technology - Translation Perceptual deficits: Retinal and acoustic prothesis in perceptual disorders (SM)

Peripheral, central sensorimotor processing: Physiology, Background and Pathophysiology (Amputees) (SM)

Technology - Translation Amputees: Bionic Hand, limb prosthetics (SM)

Spinal functioning: Physiology (GC)

Spinal cord injury (SCI): Background/Pathophysiology (GC)

Technology - Closed loop spinal neuromodulation: Introduction in Methods and Concepts (GC)

Technology - Translation SCI, MSA: Therapy of gait impairment, deficits in blood pressure modulation (GC)

Extrapyramidal control, functioning: Physiology (OB)

Extrapyramidal disorders (Parkinson's disease): Background/Pathophysiology (OB)

Technology - deep brain stimulation (DBS): Introduction in Methods and Concepts (OB)

Technology - Translation Parkinson's: DBS and focused ultrasound to treat Parkinson's symptoms (OB)

Somatosensory functioning, perceptual integration: Physiology, Background and Pathophysiology (Hallucinations) (OB)

Technology - Translation Hallucinations: Virtual reality-based technology to address hallucinations (OB)

Personalized Medicine: General Concepts of Personalized Medicine (FH)

Neuroethics: Introduction in Neuroethics (FH + ext lecturer)

Regulatory towards the Clinical Market: Introduction in important regulatory aspects (GC + ext lecturer)

Start-up: Introduction in steps towards and realities in a start-up in Neurotechnology (SM + ext lecturer)