The making of an innovative medicine
Frequency
Every year
Summary
To expose participants to translational biomedical research (from bench to bedside and back) and drug discovery.
Content
Through a logical series of presentations both from the participants and the lecturer (flipped classroom format, oral presentations, workshops) on the making of an innovative medicine, the entire and complex process starting from the therapeutic target identification up until the clinical development and use in clinical practice of a new molecular entity (NME) will be addressed and discussed.
The course is divided in twelve sections of each 2 periods of 45 minutes :
Section 1 Scope of the course, general organization, case study
Section 2 Historical perspective: the modern pharmacy
Section 3 Introduction to translational research: crossing the bridge
Section 4 Therapeutic target identification I & II
Section 5 Structure based drug design, medicinal chemistry, low/high throughput screening assays, MDOs
Section 6 Therapeutic peptides and biologicals: today's - tomorrow's pharmacy
Section 7 Personalized Healthcare (PHC) precision medicine
Section 8 Pharmacogenetic polymorphisms, Pharmacogenomics
Section 9 In vivo pharmacology, investigative toxicology
Section 10 Clinical research, phase 0, phase I, II, III, IV
Section 11 Intellectual property regulatory affairs
Section 12 Health Hackathon - Hacking medicine
Minimum 10 participants
Maximum 25 participants
Keywords
Translational biomedical research/Drug discovery
Learning Prerequisites
Required courses
Basic knowledge in Molecular Biology, Chemistry, Cellular Signaling, Pharmacology
Resources
Bibliography
"A prescription for change : the looming crisis in drug development" Pr M. Kinch UNC Press(2017) ISBN 978-1-4696-3062-5
« Histoire de la médecine » Jean Starobinsky Editions BHMS ISBN 978-2-88955-041-8
« The emperor of all maladies" Siddhartha Mukherjee Scribnee Ed. ISBN 978-1-4391-0795-9
"Drug-drug interactions" Albert Li Academic Press Ed. ISBN 0-12032944-1
Ressources en bibliothèque
Notes/Handbook
In the programs
- Number of places: 25
- Exam form: Oral presentation (session free)
- Subject examined: The making of an innovative medicine
- Lecture: 14 Hour(s)
- Exercises: 14 Hour(s)
- Number of places: 25
- Exam form: Oral presentation (session free)
- Subject examined: The making of an innovative medicine
- Lecture: 14 Hour(s)
- Exercises: 14 Hour(s)
- Number of places: 25
- Exam form: Oral presentation (session free)
- Subject examined: The making of an innovative medicine
- Lecture: 14 Hour(s)
- Exercises: 14 Hour(s)