The making of an innovative medicine
BIO-698 / 2 credits
Teacher: Clerc Roger G.
Language: English
Remark: Postponed until further notice
Frequency
Every year
Summary
To expose participants to translational research (from bench to bedside and back) and drug discovery
Content
Through a logical series of presentations both from the participants and the lecturer (flipped classroom format, oral presentations, workshops) on the making of an innovative medicine, the entire and complex process starting from the therapeutic target identification up until the clinical development and use in clinical practice of a new molecular entity (NME) will be addressed and discussed.
The course is divided in twelve sections of each 2 periods of 45 minutes :
Section 1 Scope of the course, general organization, case study
Section 2 Historical perspective: the modern pharmacy
Section 3 Introduction to translational research: crossing the bridge
Section 4 Therapeutic target identification I & II
Section 5 Structure based drug design, medicinal chemistry, low/high throughput screening assays, multiple paralell parameters optimization MDO
Section 6 Therapeutic peptides and biologicals: today's - tomorrow's pharmacy
Section 7 Personalized Healthcare (PHC) precision medicine
Section 8 Pharmacogenetic polymorphisms, Pharmacogenomics
Section 9 In vivo pharmacology, investigative toxicology
Section 10 Clinical research, phase 0, phase I, II, III, IV
Section 11 Health Hackathon - Hacking medicine I
Section 12 Health Hackathon - Hacking medicine II
Minimum 4 participants
Maximum 25 participants
Note
Please note that this course may take place in the Fall of 2020 or in the Spring of 2021.
The dates will be published in September of 2020.
Keywords
Translational biomedical research/Drug discovery
Learning Prerequisites
Required courses
Basic Molecular Biology, Cellular Signaling, Pharmacology
Resources
Bibliography
“A prescription for change : the looming crisis in drug development” Pr M. Kinch UNC Press(2017) ISBN 978-1-4696-3062-5
Ressources en bibliothèque
Notes/Handbook
In the programs
- Number of places: 25
- Exam form: Oral presentation (session free)
- Subject examined: The making of an innovative medicine
- Lecture: 14 Hour(s)
- Exercises: 14 Hour(s)
- Number of places: 25
- Exam form: Oral presentation (session free)
- Subject examined: The making of an innovative medicine
- Lecture: 14 Hour(s)
- Exercises: 14 Hour(s)
- Number of places: 25
- Exam form: Oral presentation (session free)
- Subject examined: The making of an innovative medicine
- Lecture: 14 Hour(s)
- Exercises: 14 Hour(s)