The making of an innovative medicine

Through a logical series of presentations both from the participants and the lecturer (flipped classroom format, oral presentations, workshops) on the making of an innovative medicine, the entire and complex process starting from the therapeutic target identification up until the clinical development and use in clinical practice of a new molecular entity (NME) will be addressed and discussed.

The course is divided in eleven sections of each 2 periods of 45 minutes and sections 12 & 13 of 4 periods of 45 minutes :

Section 1          Scope of the course, general organization, case study

Section 2          Historical perspective: the modern pharmacy

Section 3          Introduction to translational research: crossing the bridge

Section 4-5      Therapeutic target identification I & II

Section 6          Structure based drug design, medicinal chemistry, low/high throughput screening assays, multiple parallel parameters optimization MDO

Section 7          Therapeutic peptides and biologicals: today's - tomorrow's pharmacy NBEs

Section 8          Personalized Healthcare (PHC) precision medicine

Section 9          Pharmacogenetic polymorphisms, Pharmacogenomics

Section 10        In vivo pharmacology, investigative toxicology

Section 11        Clinical research, phase 0, phase I, II, III, IV // Intellectual property, integrity in research, my genome vs our genomes

Section 12         Health Hackathon - Hacking medicine I

Section 13         Health Hackathon - Hacking medicine II

Minimum 10 participants

Maximum 25 participants