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Coursebooks
Structure and reactivity
CH-432
Lecturer(s) :
Cramer NicolaiLanguage:
English
Summary
To develop a detailed knowledge of the key steps of advanced modern organic synthesis going beyond classical chemistry of olefins and carbonyls.Content
1. Repetition of the chemistry of olefins and carbonyls
- limitations
2. Rearrangements
- Sigmatropic: Claisen, Ireland-Claisen, Johnson-Claisen, Eschenmoser, Wittig, Evans-Mislow
- Reactive intermediates : cations, carbenes, nitrenes
3. Cyclisations and Cycloadditions
- Pericyclic reactions
- Diels-Alder (normal, hetero, inverse electron demand)
- Dipolar cycloadditions
4. Radical- and Photochemistry
5. Strrategy of Umpolung
- Stoichiometric and catalytic
6. Metal-catalysis in Organic Chemistry
- Cross-coupling and metathesis
- Olefins and C-H bonds functionalization
- Synthesis of carbo- and heterocyclic systems
Learning Outcomes
By the end of the course, the student must be able to:- Develop a detailed knowledge of the key steps of advanced modern organic synthesis going beyond classical chemistry of olefins and carbonyls
Transversal skills
- Assess one's own level of skill acquisition, and plan their on-going learning goals.
- Demonstrate the capacity for critical thinking
Teaching methods
ex cathedra lecture
Assessment methods
final oral exam
Resources
Websites
In the programs
- SemesterFall
- Exam formOral
- Credits
3 - Subject examined
Structure and reactivity - Lecture
2 Hour(s) per week x 14 weeks
- Semester
- SemesterFall
- Exam formOral
- Credits
3 - Subject examined
Structure and reactivity - Lecture
2 Hour(s) per week x 14 weeks
- Semester
Reference week
Mo | Tu | We | Th | Fr | |
---|---|---|---|---|---|
8-9 | BCH4310 | ||||
9-10 | |||||
10-11 | |||||
11-12 | |||||
12-13 | |||||
13-14 | |||||
14-15 | |||||
15-16 | |||||
16-17 | |||||
17-18 | |||||
18-19 | |||||
19-20 | |||||
20-21 | |||||
21-22 |
Lecture
Exercise, TP
Project, other
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- Autumn semester
- Winter sessions
- Spring semester
- Summer sessions
- Lecture in French
- Lecture in English
- Lecture in German