Integrative structural biology for Life sciences
BIO-643 / 2 credits
Teacher(s): Abriata Luciano Andres, Lau Kelvin Ka Ching, Pojer Florence, Various lecturers
Language: English
Frequency
Every 2 years
Summary
Theoritical and Hands-on course in biomolecular integrative structural Biology by SV specialists in the field of X-ray crystallography, Electron Microscopy, Bio-NMR and Mass Spectrometry. No previous knowledge in Structural Biology or Bioinformatic needed.
Content
This course will teach how to interpret data from major structural biology techniques and connect experimental approaches to computational modeling. You will have sessions that are tutorial based on main structural biology software as an introduction to data processing workflow.
Topics discussed in class are expected to include:
- Macromolecular X-ray crystallography
- Modeling and molecular dynamics of proteins
- Single Particle Cryo-Electron Microscopy
- Bio-NMR
- Mass Spectrometry applied to Structural Biology
Other topics may be included as needed. Lectures will be presented by the instructors and other experts at the EPFL and in the Lemanic region. Doctoral students will present in duo a 15-min. talk on a specific subject within the field at the end of the course.
Visit of structural Biology Core Facilities within EPFL will be proposed.
Note
Do not register by yourself but please contact edms@epfl.ch.
The course is open to max. 12 students and it will take place during the spring 2024.
Keywords
Macromolecular X-ray crystallography, Modeling and molecular dynamic of proteins, Single Particle Cryo-Electron Microscopy, Bio-NMR, Mass Spectrometry applied to Structural Biology.
Learning Prerequisites
Required courses
Basic molecular Biology
Bring your own laptop
Assessment methods
Oral presentation
In the programs
- Number of places: 12
- Exam form: Oral presentation (session free)
- Subject examined: Integrative structural biology for Life sciences
- Lecture: 10 Hour(s)
- Exercises: 14 Hour(s)
- Practical work: 4 Hour(s)