Cancer biology I
Summary
The course covers in detail molecular mechanisms of cancer development with emphasis on cell cycle control, genome stability, oncogenes, tumor suppressor genes, signaling pathways involved in cancer, genomic cancer analysis and rational cancer therapies.
Content
The 2x5 credit course starts in the fall semester and continues throughout the spring semester as Cancer Biology II. In the fall semester (Cancer Biology I), the following topics are covered:
-Oncogenes and tumor suppressors
-Cell cycle regulation
-Apoptosis and senescence
-Signalling pathways in cancer
-Genome maintenance and segregation
-DNA repair
-Functional genomic screens and targeted cancer therapies
-Genomic cancer analysis
Learning Prerequisites
Recommended courses
Basic knowledge of molecular biology and genetics.
Learning Outcomes
By the end of the course, the student must be able to:
- Describe the biological concepts that were discussed during the course.
- Analyze the experiments and conclusions that were covered in the discussed papers and the exercises.
- Design experimental approaches to tackle scientific questions.
Teaching methods
Ex cathedra and exercices
Assessment methods
written exam during the winter session
Supervision
| Others | Office hours by appointment only. |
Resources
Bibliography
Robert A. Weinberg: The Biology of Cancer, 3rd edition 2023, Norton & Company, ISBN 978-0-393-88766-2
Ressources en bibliothèque
Moodle Link
In the programs
- Semester: Fall
- Exam form: During the semester (winter session)
- Subject examined: Cancer biology I
- Courses: 3 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: During the semester (winter session)
- Subject examined: Cancer biology I
- Courses: 3 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Fall
- Exam form: During the semester (winter session)
- Subject examined: Cancer biology I
- Courses: 3 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks
- Type: optional