EE-518 / 3 credits

Teacher(s): Carrara Sandro, Schmid Alexandre, Skrivervik Anja

Language: English


Summary

Introduction to analog CMOS design for Remote Biosensors on Chip. Understanding and designing of active and remotely powered biosensing systems. Basic understanding of the wireless transmission of the obtained signals.

Content

Introduction to Analog design for Brain/CMOS interfaces

Principles of Electrochemical Biosensing: Target/Probe Interactions; Amperometric, Potentiometric, Capacimetric, and Impedimetric sensing

Electrochemical cell and related equivalent circuits

Basic CMOS configurations for electrochemical biosensing and related analog circuits

Wireless transmission in lossy media: issues on temperature, specific absorption rate (SAR) and efficiency. Antennas for such devices

Regulation aspects of wireless transmission close or in living matter: maximum value of the SAR and the temperature with respect to the frequency of operation and the body tissue.

Architecture of a biomedical implant and major blocks

Fundamentals of biomedical data transmission, data transmitters (active transmitters for RF communication)

Passive data transmitters (backscattering, load modulation), data receivers

Remote powering of implants (types and inductive remote powering, battery charging)

Data conditioning (spike detection, compression)

Keywords

OpAmp, CMOS, biosensors, RF communication, Remote Powering, wireless transmission

Learning Prerequisites

Required courses

Electronics I and II

Learning Outcomes

By the end of the course, the student must be able to:

  • Design complete devices for remote biosensing at system level
  • Design simple analog circuits for the biosensor frontend
  • Design simple analog circuits for the RF data communication
  • Design simple analog circuits for the remote powering operation
  • Assess / Evaluate appropriate sources of information

Teaching methods

ex cathedra with supevised exercises

Assessment methods

exam

In the programs

  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Analog circuits for biochip
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 1 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Analog circuits for biochip
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 1 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Analog circuits for biochip
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 1 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Analog circuits for biochip
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 1 Hour(s) per week x 14 weeks
  • Type: optional

Reference week

Tuesday, 10h - 12h: Lecture ELD120

Tuesday, 12h - 13h: Exercise, TP ELD120

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