Advanced biomedical imaging methods and instrumentation
PHYS-719 / 4 credits
Teacher(s): Hyacinthe Jean-Noël, Invited lecturers (see below), Mishkovsky Mor-Miri
Language: English
Remark: Next time: Fall
Frequency
Every year
Summary
The main goal of this course is to give the student a solid introduction into approaches, methods, and instrumentation used in biomedical research. A major focus is on Magnetic Resonance Imaging (MRI) and related methods, but other imaging modalities will be increasingly covered.
Content
The course will cover the following topics by experts of each field:
Introduction (Bloch equations; Components of an MRI systems; Peamplifier, ADC;Longitudinal interference)
MRI basics (Spin-warp imaging, slice selection, EPI;Fourier image reconstruction, zero-filling apodization; -space
imaging strategies - what defines contrast;Gibbs ringing and other artefacts)
Hardware of imaging (Gradient coils - eddy currents; Shimming: Theory of coil design, spherical harmonics; field
mapping and shim methods)
Localization methods for MRS (ISIS, PRESS, STEAM;Chemical shift displacement error;Water suppression
methods, fat suppression methods, dynamic range)
Multinuclear MRS in an inhomogeneous RF field (Localization methods (PT, DEPT, HH);Decoupling, WALTZ,
adiabatic decoupling;Adiabatic RF pulses;Absolute quantification (water, external, internal))
Moving magnetization (Artifact recognition - bases of artifacts; 2nd moment nulling, PC flow imaging, TOF;
Triggering and synchronization)
Diffusion MR(Stejskal-tanner, b value, Einstein-stokes relationship; Restricted vs. hindered diffusion; q-space
imaging; DTI and fiber tracking)
Perfusion imaging(Pulsed arterial spin labeling, FAIR, EPISTAR;Continuous arterial spin labeling)
Magnetization transfer(MTC imaging, Solomon equations;Saturation transfer experiments)
Rf coils(Theory of matching;Coil design surface coil TEM coil;Diel effects, coil loading and efficiency)
Imaging sequences (STEAM, SE, FSE (CPMG), FLASH, SSFP)
fMRI(BOLD effect, SE vs GE imaging;Pharmacological MRI;Biophysical basis)
Modeling (Tracer kinetics;Uptake curves)
Dr. Vladimír Mlynárik - 2h
Prof. Ileana Jelescu - 2h
Dr. Daniel Wenz - 2h
Dr. Yohan van de Looij - 2h
Dr. Ruud van Heeswijk - 2h
Prof. Valerio Zerbi - 2h
Prof. Jessica Bastiaansen - 2h
Dr. Hikari Yoshihara - 2h
Dr. Andrea Capozzi - 1h
Dr. Bernard Lanz - 2h
Dr. Lijing Xin - 2h Dr. Thanh Phong Lê 2h
Note
Above program is preliminary and for the current year only. May change to include other modalities as well in future years. 80% presence in class is mandatory.
Keywords
spin physics, MRI, RF engineering
Learning Prerequisites
Required courses
Course(s) attended, equivalent to the teaching of "fundamentals of biomedical imaging" or practical exposure to the topics covered in this course as part of the PhD for at least 6 months. In other words, the student should be familiar with the basics of the imaging methodologies covered.
In the programs
- Exam form: Term paper (session free)
- Subject examined: Advanced biomedical imaging methods and instrumentation
- Lecture: 28 Hour(s)
- Exercises: 28 Hour(s)
- Type: optional
- Exam form: Term paper (session free)
- Subject examined: Advanced biomedical imaging methods and instrumentation
- Lecture: 28 Hour(s)
- Exercises: 28 Hour(s)
- Type: optional
- Exam form: Term paper (session free)
- Subject examined: Advanced biomedical imaging methods and instrumentation
- Lecture: 28 Hour(s)
- Exercises: 28 Hour(s)
- Type: optional
- Exam form: Term paper (session free)
- Subject examined: Advanced biomedical imaging methods and instrumentation
- Lecture: 28 Hour(s)
- Exercises: 28 Hour(s)
- Type: optional