CH-438 / 3 crédits

Enseignant: Zhu Jieping

Langue: Anglais


Summary

Complex polycyclic natural products are chosen to illustrate the evolution of the state-of-the-art of the field, the interplay between strategy and new reactions as well as the importance of implementing multi-bond forming processes in a synthesis.

Content

Retro-synthesis and synthesis of different classes of natural products important for their structure and/or bioactivity.

Keywords

Retro-synthetic analysis, Synergism between strategy and new reactions, Domino reactions, multicomponent reactions, Oxidative coupling, Pattern Recognition, Hidden Symmetry, C-H Functionalization, Asymmetric organocatalysis

 

Learning Prerequisites

Recommended courses

General knowledge of organic reactions. Basic knowledge of retro-syntheis. EPFL lectures fonctions et réactions organiques I and II, synthèse asymétrique, target synthesis, structure and reactivity or equivalent courses.

Learning Outcomes

By the end of the course, the student must be able to:

  • Draw reaction mechanism
  • Analyze synthetic route
  • Elaborate synthetic scheme
  • Design synthetic strategy

Supervision

Office hours Yes
Assistants Yes
Forum Yes

Dans les plans d'études

  • Semestre: Automne
  • Forme de l'examen: Ecrit (session d'hiver)
  • Matière examinée: Total synthesis of natural products
  • Cours: 2 Heure(s) hebdo x 14 semaines
  • Type: optionnel
  • Semestre: Automne
  • Forme de l'examen: Ecrit (session d'hiver)
  • Matière examinée: Total synthesis of natural products
  • Cours: 2 Heure(s) hebdo x 14 semaines
  • Type: optionnel
  • Forme de l'examen: Ecrit (session d'hiver)
  • Matière examinée: Total synthesis of natural products
  • Cours: 2 Heure(s) hebdo x 14 semaines
  • Type: optionnel

Semaine de référence

Cours connexes

Résultats de graphsearch.epfl.ch.