Supramolecular chemistry

Summary

The course provides an introduction to supramolecular chemistry. In addition, current trends are discussed using recent publications in this area.

Content

Learning Outcomes

By the end of the course, the student must be able to:

• Recall the most important non-covalent interactions.
• Recall analytical techniques for the analysis of host-guest systems.
• Assess / Evaluate the thermodynamic driving force for the formation of self-assembled systems.
• Recall the most important classes of receptors for anions, cations, and neutral molecules.
• Recall the design principles for the construction of metallasupramolecular aggregates.
• Differentiate rotaxanes, pseudorotaxanes, catenenaes and molecular knots and machines, and recall synthetic routes to make these compounds
• Recall attempts for the bottom-up construction of molecular machines.
• Describe the basic concepts of self-replicating molecules, molecular imprinting, foldamers, and selection experiments with dynamic combinatorial libraries.

Expected student activities

Summarize and discuss a recently published research article in the area of supramolecular chemistry in form of a Powerpoint presentation.

Assessment methods

Written exam during the course (50%)

Oral presentation during the course (50%)

Resources

Ressources en bibliothèque

• Supramolecular Chemistry / Steed
• Principles and Methods in Supramolecular Chemistry / Schneider

Moodle Link

• https://go.epfl.ch/CH-424