BIO-392 / 4 crédits

Enseignant(s): Constam Daniel, De Palma Michele

Langue: Anglais


Summary

This course provides a comprehensive overview of the biology of cancer, illustrating the mechanisms that cancer cells use to grow and disseminate at the expense of normal tissues and organs. The “hallmarks of cancer” categorization proposed by Hanahan and Weinberg (2001; 2011) provides a referen

Content

Keywords

cancer; hallmark of cancer; oncogene; tumor suppressor; tumor microenvironment; tumor immunology; tumor angiogenesis; invasion; metastasis; targeted therapy; resistance mechanism

Learning Prerequisites

Required courses

Biology

Important concepts to start the course

The biology of the cell, including: transcription; cell signaling; cell cycle.

Learning Outcomes

By the end of the course, the student must be able to:

  • Conduct a study to identify the mechanism(s) of tumorigenesis
  • Assess / Evaluate the molecular and cellular mechanisms of tumorigenesis
  • Design mechanism-targeted treatments to inhibit tumorigenesis

Transversal skills

  • Summarize an article or a technical report.
  • Give feedback (critique) in an appropriate fashion.
  • Access and evaluate appropriate sources of information.
  • Take feedback (critique) and respond in an appropriate manner.

Teaching methods

Lectures, during which the feedback of the students is requested.

Exercises (can vary in style, but are important to reach the learning objectives)

Expected student activities

Attending lectures and exercises.

Assessment methods

Written exam

Resources

Bibliography

The biology of cancer, Ed. Garland Science (by R. A. Weinberg).

Hallmarks of Cancer: The next generation. In Cell, 2011 (by D. Hanahan and R. A. Weineberg)

Ressources en bibliothèque

Dans les plans d'études

  • Semestre: Printemps
  • Forme de l'examen: Ecrit (session d'été)
  • Matière examinée: Oncology
  • Cours: 2 Heure(s) hebdo x 14 semaines
  • Exercices: 2 Heure(s) hebdo x 14 semaines

Semaine de référence

 LuMaMeJeVe
8-9     
9-10     
10-11     
11-12     
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22