Infection biology
Summary
Infectious diseases (ID) are still a major problem to human health. But how do pathogens make us sick? How do they evolve and spread? The discovery and use of antibiotics and vaccination has changed the outcome of some IDs. But resistance mechanisms have evolved and are of major concern.
Content
- Impact of infectious diseases (pandemics, epidemics)
- Evolution of pathogens and horizontal gene transfer
- Bacterial infections (intra vs. extracellular bacteria)
- Virulence factors inclduing toxins and secretion systems
- Identification of virulence factors using molecular approaches
- (Emerging) infectious diseases in the context of Planetary Health
- Diarrheal diseases
- Respiratory diseases
- Viral infections
- Symbiosis
- Microbiota
- Vaccines
- Antimicrobials and resistances
- Eukaryotic pathogens including pathogenic fungi
- Bioethical aspects of ID research
Keywords
Infection Biology; bacterial pathogens; viruses; eukaryotic pathogens; antibiotics and resistance mechanisms; virulence factors; global impact of infectious diseases.
Learning Prerequisites
Recommended courses
Basic microbiology (requirement), immunology, basic cell biology, and genetics and genomics.
Important concepts to start the course
Background knowledge in microbiology.
Teaching methods
Ex cathedra + exercises, including presentation and discussion of relevant scientific publications.
Expected student activities
Students are expected to participate in this course by attending all class sessions including the journal clubs. Students will present and discuss recent state-of-the-art publications in depths.
Assessment methods
During the semester (presentation + continous control exam)
Supervision
| Office hours | No |
| Assistant.e.s | Yes |
| Forum | No |
| Others |
Resources
Bibliography
- "Bacterial pathogenesis: a molecular approach / Brenda A. Wilson ... [et al.]. Year:2011.
- ISBN:978-1-55581-418-2
- "Microbiology: an evolving science / Joan L. Slonczewski, John W. Foster. Year:2011.
- ISBN:978-0-393-11824-7
- "Principles of virology" / S.J. Flint ... [et al.]. Year:2009. ISBN:978-1-55581-443-4
Ressources en bibliothèque
Moodle Link
Dans les plans d'études
- Semestre: Printemps
- Forme de l'examen: Pendant le semestre (session d'été)
- Matière examinée: Infection biology
- Cours: 3 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Type: optionnel
- Semestre: Printemps
- Forme de l'examen: Pendant le semestre (session d'été)
- Matière examinée: Infection biology
- Cours: 3 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Type: optionnel
- Semestre: Printemps
- Forme de l'examen: Pendant le semestre (session d'été)
- Matière examinée: Infection biology
- Cours: 3 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Type: optionnel
Semaine de référence
| Lu | Ma | Me | Je | Ve | |
| 8-9 | |||||
| 9-10 | |||||
| 10-11 | |||||
| 11-12 | |||||
| 12-13 | |||||
| 13-14 | |||||
| 14-15 | |||||
| 15-16 | |||||
| 16-17 | |||||
| 17-18 | |||||
| 18-19 | |||||
| 19-20 | |||||
| 20-21 | |||||
| 21-22 |
Légendes:
Cours
Exercice, TP
Projet, Labo, autre