BIO-477 / 5 crédits

Enseignant: Blokesch Melanie

Langue: Anglais


Summary

Infectious diseases (ID) are still a major problem to human health. But how do pathogens make us sick? How do they evolve and spread? The discovery and use of antibiotics and vaccination has changed the outcome of some IDs. But resistance mechanisms have evolved and are of major concern.

Content

  • Impact of infectious diseases (pandemics, epidemics)
  • Evolution of pathogens and horizontal gene transfer
  • Bacterial infections (intra vs. extracellular bacteria)
  • Virulence factors inclduing toxins and secretion systems
  • Identification of virulence factors using molecular approaches
  • (Emerging) infectious diseases in the context of Planetary Health
  • Diarrheal diseases
  • Respiratory diseases
  • Viral infections
  • Symbiosis
  • Microbiota
  • Vaccines
  • Antimicrobials and resistances
  • Eukaryotic pathogens including pathogenic fungi
  • Bioethical aspects of ID research

Keywords

Infection Biology; bacterial pathogens; viruses; eukaryotic pathogens; antibiotics and resistance mechanisms; virulence factors; global impact of infectious diseases.

 

Learning Prerequisites

Recommended courses

Basic microbiology (requirement), immunology, basic cell biology, and genetics and genomics.

 

Important concepts to start the course

Background knowledge in microbiology.

Teaching methods

Ex cathedra + exercises, including presentation and discussion of relevant scientific publications.

 

Expected student activities

Students are expected to participate in this course by attending all class sessions including the journal clubs. Students will present and discuss recent state-of-the-art publications in depths.

 

Assessment methods

During the semester (presentation + continous control exam)

Supervision

Office hours No
Assistant.e.s Yes
Forum No
Others

Resources

Bibliography

  • "Bacterial pathogenesis: a molecular approach / Brenda A. Wilson ... [et al.]. Year:2011.
  • ISBN:978-1-55581-418-2
  • "Microbiology: an evolving science / Joan L. Slonczewski, John W. Foster. Year:2011.
  • ISBN:978-0-393-11824-7
  • "Principles of virology" / S.J. Flint ... [et al.]. Year:2009. ISBN:978-1-55581-443-4

Ressources en bibliothèque

Moodle Link

Dans les plans d'études

  • Semestre: Printemps
  • Forme de l'examen: Pendant le semestre (session d'été)
  • Matière examinée: Infection biology
  • Cours: 3 Heure(s) hebdo x 14 semaines
  • Exercices: 2 Heure(s) hebdo x 14 semaines
  • Type: optionnel
  • Semestre: Printemps
  • Forme de l'examen: Pendant le semestre (session d'été)
  • Matière examinée: Infection biology
  • Cours: 3 Heure(s) hebdo x 14 semaines
  • Exercices: 2 Heure(s) hebdo x 14 semaines
  • Type: optionnel
  • Semestre: Printemps
  • Forme de l'examen: Pendant le semestre (session d'été)
  • Matière examinée: Infection biology
  • Cours: 3 Heure(s) hebdo x 14 semaines
  • Exercices: 2 Heure(s) hebdo x 14 semaines
  • Type: optionnel

Semaine de référence

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