Fiches de cours

Immunoengineering

BIOENG-399

Enseignant(s) :

Tang Li

Langue:

English

Withdrawal

It is not allowed to withdraw from this subject after the registration deadline.

Summary

Immunoengineering is an emerging field where engineering principles are grounded in immunology. This course provides students a broad overview of how engineering approaches can be utilized to study immunology, model immune systems, modulate immune response, and develop novel immunotherapies.

Content

 

Part 1. Understanding immunology with engineering tools

Introduction of the course and expectation

Overview of the fundamentals of immunology

Definition and scope of immunoengineering

Engineering tools and new technologies to understand immunology

Modeling lymphoid tissues

 

Part 2. Engineering novel immunotherapies for diseases

Cancer and cancer immunotherapies

Concept and overview of drug delivery

Materials engineering in the advancement of immunotherapies

Immune cell engineering and genetic engineering

Metabolic engineering and immune modulation

Overview of adaptive immunity and vaccines

Design of immunogenic vaccines

Cell based vaccines

Autoimmunity and tolerogenic vaccines

Protein and antibody engineering

 

Part 3. Applications and practical issues

Considerations on immune drug discovery and development

Keywords

immunology, immunoengineering, vaccines, infectious diseases, autoimmunity, cancer, materials engineering, drug delivery, protein engineering, drug discovery and development

Learning Prerequisites

Required courses

Physiologie par systèmes I

Learning Outcomes

By the end of the course, the student must be able to:

• Describe the concept of immunoengineering
• Make examples of how engineering approaches has led to advancements in immunotherapy
• Take into consideration how to apply engineering principles to immunology research and applications

Transversal skills

• Summarize an article or a technical report.
• Communicate effectively, being understood, including across different languages and cultures.
• Write a scientific or technical report.

Teaching methods

Lectures integrated with exercises

 

Expected student activities

Attending lectures, analysing figures from research papers, completing exercises, paper discussion, reading and presenting scientific literatures.

Assessment methods

Exercise: 30%

Final written exam: 70%

Supervision

Office hours	Yes
Assistants	Yes
Forum	Yes

Resources

Bibliography

Library resources

How the immune system works: Lauren Sompayrac. 3e

Kuby Immunology: Owen, Pung, Stranford. 7e

Cellular and Molecular Immunology: Abbas & Lichtman. 8e  

Janeway's immunobiology: Kenneth Murphy ; Charles A. Janeway ; Allan Mowat. 8e

Ressources en bibliothèque

• How the immune system works / Sompayrac
• Kuby Immunology / Pung
• Cellular and Molecular Immunology / Abbas
• Janeway's immunobiology / Murphy