BIOENG-611 / 2 crédits

Enseignant(s): Manley Suliana, Smith Ana-Suncana

Langue: Anglais

Remark: Lectures would take place on Oct 2, 3, 4, 6, and there will be one day free for a project/exercise work on Oct 5.


Frequency

Only this year

Summary

This course introduces students to models of active and passive transport in biological systems. This will include the effect of external factors (motor proteins, crowding) and membrane dynamics on transportation. Finally, the course will cover the emergence of intracellular collective motion.

Content

The goal of this course is to develop theoretical models for transport corresponding cases of particular interest in biological systems. Starting from a review of first-principles concepts behind transport and diffusion, students will learn how to model active and passive transport. This will include the effect of external factors on transportation dynamics, such as forces exerted by motor proteins and macromolecular crowding. In addition, the course will discuss the roles of geometry and membrane dynamics of organelles. Finally, we will cover the emergence of collective movements of intracellular components.

Note

Maximum number of participants: 20

Keywords

Intracellular transport, active transport, diffusion, motor proteins, crowding, membrane dynamics, collective motion

Learning Prerequisites

Required courses

Basic understanding of classical mechanics and statistical physics is beneficial.

Learning Outcomes

By the end of the course, the student must be able to:

  • Model diffusion and active transport of intracellular components
  • Assess / Evaluate the validity of a model given experimental conditions
  • Apply these models to practical cases

Resources

Bibliography

P. Nelson: Biological Physics

Ressources en bibliothèque

Moodle Link

Dans les plans d'études

  • Nombre de places: 20
  • Forme de l'examen: Exposé (session libre)
  • Matière examinée: Diffusion in biological systems
  • Cours: 28 Heure(s)
  • Projet: 8 Heure(s)
  • Type: optionnel

Semaine de référence

Cours connexes

Résultats de graphsearch.epfl.ch.