Biomaterials and tissue engineering
Summary
This course covers the fundamental concepts of the design, function and application of state-of-the-art biomaterials, and an overview of how engineering approaches can be used to investigate and manipulate cell and tissue functions.
Content
Introduction
Part I: Biological fundamentals
Cells, extracellular matrices and tissues
Proteins and protein adsorption, immunological aspects of biomaterials
Part II: Biomaterials classes
Biomaterials for devices, structural and chemically degradable biomaterials
Micro- and nanoparticles
Extracellular matrix-mimicking biomaterials
Hydrogels as biomaterials
Self-assembly and supramolecular biomaterials
Part III: Emerging design and applications of biomaterials
Tailoring materials for stem cell biology
Biomaterials for neuroengineering
Biomaterials in medical devices
Macro-materials for tissue engineering
Micro-/nano-materials for drug delivery
Part IV: Specific topics
Immune tissue engineering
Soft tissue engineering (skin)
Airway tissue engineering
Tissue engineering for cancer
Organoids
Part V: Presentations of group projects
Learning Prerequisites
Required courses
None.
Recommended courses
BIOEING-399 Immunoengineering
BIOENG-315 Materials science for bioengineers
Important concepts to start the course
This class requires a basic knowledge in biology, physics, chemistry, and materials science.
Learning Outcomes
By the end of the course, the student must be able to:
- Elaborate key effectors and their functions driving protein- and cell-materials interactions
- Formulate the basics of inflammation induced by materials in the body
- Elaborate the basics of stem cell function and tissue regeneration, and how materials can influence regeneration
- Systematize the different general applications of biomaterials
- Contextualise specific examples of biomaterials on the basis of application and understands their selection criteria
- Judge the suitability of a material for a certain application based on structure-property relationships
- Formalize the key concepts in the molecular engineering of bioactivity and bioresponsiveness
Transversal skills
- Assess one's own level of skill acquisition, and plan their on-going learning goals.
- Make an oral presentation.
- Demonstrate a capacity for creativity.
- Continue to work through difficulties or initial failure to find optimal solutions.
- Evaluate one's own performance in the team, receive and respond appropriately to feedback.
- Communicate effectively, being understood, including across different languages and cultures.
- Use a work methodology appropriate to the task.
- Set objectives and design an action plan to reach those objectives.
- Plan and carry out activities in a way which makes optimal use of available time and other resources.
Teaching methods
Lectures integrated with exercises
Group case study
Assessment methods
Group project: 40%
Final written exam: 60%
Supervision
Office hours | Yes |
Assistants | Yes |
Forum | Yes |
Dans les plans d'études
- Semestre: Printemps
- Forme de l'examen: Ecrit (session d'été)
- Matière examinée: Biomaterials and tissue engineering
- Cours: 2 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Semestre: Printemps
- Forme de l'examen: Ecrit (session d'été)
- Matière examinée: Biomaterials and tissue engineering
- Cours: 2 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Semestre: Printemps
- Forme de l'examen: Ecrit (session d'été)
- Matière examinée: Biomaterials and tissue engineering
- Cours: 2 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Semestre: Printemps
- Forme de l'examen: Ecrit (session d'été)
- Matière examinée: Biomaterials and tissue engineering
- Cours: 2 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines
- Semestre: Printemps
- Forme de l'examen: Ecrit (session d'été)
- Matière examinée: Biomaterials and tissue engineering
- Cours: 2 Heure(s) hebdo x 14 semaines
- Exercices: 2 Heure(s) hebdo x 14 semaines