The making of an innovative medicine


Lecturer(s) :

Clerc Roger G.




Every year


Postponed until further notice


To expose participants to translational research (from bench to bedside and back) and drug discovery


Through a logical series of presentations both from the participants and the lecturer (flipped classroom format, oral presentations, workshops) on the making of an innovative medicine, the entire and complex process starting from the therapeutic target identification up until the clinical development and use in clinical practice of a new molecular entity (NME) will be addressed and discussed.


The course is divided in twelve sections of each 2 periods of 45 minutes :

Section 1          Scope of the course, general organization, case study

Section 2          Historical perspective: the modern pharmacy

Section 3          Introduction to translational research: crossing the bridge

Section 4          Therapeutic target identification I & II

Section 5          Structure based drug design, medicinal chemistry, low/high throughput screening assays, multiple paralell parameters optimization MDO

Section 6          Therapeutic peptides and biologicals: today's - tomorrow's pharmacy

Section 7          Personalized Healthcare (PHC) precision medicine

Section 8          Pharmacogenetic polymorphisms, Pharmacogenomics

Section 9          In vivo pharmacology, investigative toxicology

Section 10         Clinical research, phase 0, phase I, II, III, IV

Section 11         Health Hackathon - Hacking medicine I

Section 12         Health Hackathon - Hacking medicine II


Minimum 4 participants

Maximum 25 participants


Please note that this course may take place in the Fall of 2020 or in the Spring of 2021.

The dates will be published in September of 2020.


Translational biomedical research/Drug discovery

Learning Prerequisites

Required courses

Basic Molecular Biology, Cellular Signaling, Pharmacology



'A prescription for change : the looming crisis in drug development' Pr M. Kinch UNC  Press(2017) ISBN 978-1-4696-3062-5

Ressources en bibliothèque



In the programs

Reference week

      Exercise, TP
      Project, other


  • Autumn semester
  • Winter sessions
  • Spring semester
  • Summer sessions
  • Lecture in French
  • Lecture in English
  • Lecture in German