BIO-372 / 4 credits
Teacher: McKinney John
This course will provide an introduction to fundamental concepts in microbiology. Special emphasis will be given to the surprising and often counter-intuitive physical world inhabited by microorganisms.
• The unexpected physics of being small
• Microbial cell structure, inside and out
• Microscale forces and microbial form
• Transmembrane transport phenomena
• Biomechanics of microbial appendages
• Microbial motility and microscale fluid mechanics
• Microbial taxis - random walks and directed motion
• Global nutrient and redox cycles
• Microbial metabolic symbiosis
• Symmetry breaking in microbial differentiation
• Molecular noise and microbial individuality
• Genetic networks and synthetic microbiology
• Fundamentals of virology
Cycle propédeutique (semestres 1 et 2) et cycle bachelor (semestres 3 et 4) en Sciences et Technologies du Vivant
Fluid Mechanics for SV, Structural Mechanics
By the end of the course, the student must be able to:
- Explain how microscale forces shape the basic structure of microbial cells
- Explain the mechanics of non-Hookean biomaterials in microbial cell functions
- Explain how low Reynolds number fluid dynamics affect microbial motility
- Explain how low Péclet number transport phenomena affect microbial taxis
- Explain the selectivity of material exchanges between microbes and their environments
- Explain the essential roles of microorganisms in global nutrient and redox cycling
- Explain the molecular and physiological bases of microbial metabolic symbioses
- Explain some of the symmetry-breaking strategies involved in microbial differentiation
- Explain the role of molecular fluctuations in microbial non-ergodic phenotypic variation
- Explain the logic of microbial genetic networks in basic engineering terms
- Explain fundamental concepts in replication and pathogenesis of viruses
- Access and evaluate appropriate sources of information.
- Summarize an article or a technical report.
- Take responsibility for environmental impacts of her/ his actions and decisions.
- Respect the rules of the institution in which you are working.
- Communicate effectively, being understood, including across different languages and cultures.
- Use a work methodology appropriate to the task.
Lectures and group exercises
Expected student activities
Attendance of lectures, completion of written exercises in small working groups
Written exam of 3 hours comprising 14 answers in short-essay format based on 14 questions (2 per week) selected from a list of 28 questions.
In the programs
- Semester: Spring
- Exam form: During the semester (summer session)
- Subject examined: Microbiology
- Lecture: 2 Hour(s) per week x 14 weeks
- Exercises: 2 Hour(s) per week x 14 weeks