BIOENG-519 / 4 credits

Teacher(s): Mangeat Bastien, Iseli Christian, Pojer Florence, Garcia Miguel, Chrast Roman, Pavlou Maria

Language: English

Withdrawal: It is not allowed to withdraw from this subject after the registration deadline.


Summary

High-throughput methodologies broadly called Omics allow to characterize the complexity and dynamics of any biological system. This course will provide a general description of different methods related to the Omics field followed by hands-on rotations in participating technological platforms.

Content

Keywords

Omics (including single cell omics)

Bioinformatics

Quality control

Data analysis

Data interpretation

Learning Prerequisites

Required courses

BSc in Life Sciences and Technology or Bioengineering program

 

Learning Outcomes

By the end of the course, the student must be able to:

  • Choose appropriate Omics technique(s) to design relevant experiment
  • Apply the concept of data quality control
  • Interpret the generated data
  • Contextualise theoritical and technical concepts of covered Omics techniques

Transversal skills

  • Use a work methodology appropriate to the task.
  • Collect data.
  • Plan and carry out activities in a way which makes optimal use of available time and other resources.
  • Evaluate one's own performance in the team, receive and respond appropriately to feedback.

Teaching methods

This course will be divided into 5 weeks of theoretical lectures followed by 8 weeks of rotations in participating scientific platforms including Protein Production and Structure, Flow Cytometry, Gene Expression, Proteomics and Bioinformatics. For the platform rotationspart, students will work in small groups (max 6 students per group) and will perform experimental work in two different platforms (platform 1: weeks 6 to 8 and platform 2: weeks 9 to 11) followed by a common rotation at the bioinformatics platform (all students together, week 12-13). Regarding the selection of platforms for rotations: we will try to accommodate as much as possible students preferences. The last week (week 14) will be dedicated to the preparation of the lab reports and to the final exam.

Expected student activities

Lectures

Hands-on practical work during 3 rotations in participating platforms

Reading articles

Project presentations

Assessment methods

Written reports covering 2 rotations in platforms and written exam during the last week of the semester.

 

Supervision

Office hours Yes
Assistants Yes
Forum No

In the programs

  • Semester: Fall
  • Number of places: 24
  • Exam form: During the semester (winter session)
  • Subject examined: Methods: omics in biomedical research
  • Lecture: 1 Hour(s) per week x 14 weeks
  • Practical work: 3 Hour(s) per week x 14 weeks
  • Semester: Fall
  • Number of places: 24
  • Exam form: During the semester (winter session)
  • Subject examined: Methods: omics in biomedical research
  • Lecture: 1 Hour(s) per week x 14 weeks
  • Practical work: 3 Hour(s) per week x 14 weeks

Reference week

 MoTuWeThFr
8-9    CO120
9-10    CO120
10-11    
11-12    
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     

Friday, 8h - 9h: Lecture CO120

Friday, 9h - 12h: Exercise, TP CO120