BIOENG-519 / 4 credits

Teacher(s): Chrast Roman, Garcia Miguel, Guex Nicolas Jean Philippe, Iseli Christian, Mangeat Bastien, Pavlou Maria, Pojer Florence

Language: English

Withdrawal: It is not allowed to withdraw from this subject after the registration deadline.


Summary

High-throughput methodologies broadly called Omics allow to characterize the complexity and dynamics of any biological system. This course will provide a general description of different methods related to the Omics field followed by hands-on rotations in participating technological platforms.

Content

Keywords

Omics (including single cell omics)

Bioinformatics

Quality control

Data analysis

Data interpretation

Learning Prerequisites

Required courses

BSc in Life Sciences and Technology or Bioengineering program

 

Learning Outcomes

By the end of the course, the student must be able to:

  • Choose appropriate Omics technique(s) to design relevant experiment
  • Apply the concept of data quality control
  • Interpret the generated data
  • Contextualise theoretical and technical concepts of the covered Omics techniques

Transversal skills

  • Use a work methodology appropriate to the task.
  • Collect data.
  • Plan and carry out activities in a way which makes optimal use of available time and other resources.
  • Evaluate one's own performance in the team, receive and respond appropriately to feedback.

Teaching methods

This course will be divided into 3 weeks of common theoretical lectures followed by 11 weeks of rotations in participating scientific platforms including Protein Production and Structure, Flow Cytometry, Gene Expression, Proteomics and Bioinformatics. For the platform rotations part, students will work in small groups (max 6 students per group) and will perform experimental work in Protein Production and Purification, Flow Cytometry, Gene Expression and Proteomics platforms (2 weeks / platform) followed by a common rotation at the bioinformatics platform (all students together, week 12-14).

Expected student activities

Lectures

Hands-on practical work during 5 rotations in participating platforms

Reading articles

Project presentation

 

Assessment methods

Evaluation (written reports or oral presentations) covering platform rotations and written exam during exam session.

 

Supervision

Office hours Yes
Assistants Yes
Forum No

In the programs

  • Semester: Fall
  • Number of places: 24
  • Exam form: Written (winter session)
  • Subject examined: Methods: omics in biomedical research
  • Lecture: 1 Hour(s) per week x 14 weeks
  • Practical work: 3 Hour(s) per week x 14 weeks
  • Semester: Fall
  • Number of places: 24
  • Exam form: Written (winter session)
  • Subject examined: Methods: omics in biomedical research
  • Lecture: 1 Hour(s) per week x 14 weeks
  • Practical work: 3 Hour(s) per week x 14 weeks

Reference week

 MoTuWeThFr
8-9     
9-10     
10-11     
11-12     
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     

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