ENV-621 / 3 credits

Teacher(s): Altshuler Ianina, Bell Emma, Bernier-Latmani Rizlan, Carratala Ripolles Anna

Language: English

Remark: Next time: 2026


Frequency

Every 3 years

Summary

This course will train doctoral students to use bioinformatic tools to analyse amplicon and metagenomic sequences. In addition, we will also touch upon meta-transcriptomics and meta-proteomics.

Content

Theory:
Introduction to Omics and DNA sequencing technologies
DNA sequencing and uncultured microorganisms
Reproducible research and community standards
Metagenome sequence assembly overview
Intro to read mapping and mapping tools
Reconstructing genomes from metagenomes
Intro to Annotation, databases, HMMs

 

Practical:
Intro to command line / computing resources
QC reads, Adaptor Removal
Assembly
Assembly stats
Gene prediction
Mapping
Binning
Bin refinement
Bin QC
Dereplication
Abundance
GTDB
Phylogenomics
Functional Annotation

Note

Dr. Emma Bell

Resources

Moodle Link

In the programs

  • Number of places: 20
  • Exam form: Oral presentation (session free)
  • Subject examined: Hands-on bioinformatics for microbial meta-omics
  • Lecture: 40 Hour(s)
  • Practical work: 40 Hour(s)
  • Type: optional

Reference week

Related courses

Results from graphsearch.epfl.ch.