Cancer biology II

BIO-472 / 5 credits

Teacher(s): De Palma Michele, Hülsken Jörg

Language: English

Summary

The course covers in detail the interactions of cancer cells with their environment with an emphasis on tumor-angiogenesis, inflammation, adaptive and innate immunity and cancer-induced immune suppression. Additional topics are cancer metabolism, cancer stem cells and metastasis.

Content

The 2x5 credit course Cancer Biology I+II starts in the winter semester and continues throughout the summer semester.

Cancer Biology II covers:

  • complex oncogenic signaling networks and hierarchical tumor organization
  • tumor metabolism
  • cell death signaling and apoptosis
  • cancer histology with pratical training
  • inflammatory signaling in cancer
  • tumor angiogenesis
  • tumor cell dissemination and metastasis
  • innate immunity: pro-tumorigenic roles of inflammation, NK cells
  • adaptive immunity: immuno editing, immune evasion, immunotherapy

The weekly lectures will be followed by exercises. The task for these exercises will be student presentations of scientific articles which illustrate the course in order to consolidate the knowledge of the course topics.

Learning Prerequisites

Recommended courses

Cancer Biolgy I

Immunology

Assessment methods

Continuous evaluation during the semester with two intermediate exams

Resources

Bibliography

The Biology of Cancer, Robert A. Weinberg

Ressources en bibliothèque

Moodle Link

In the programs

  • Semester: Spring
  • Exam form: During the semester (summer session)
  • Subject examined: Cancer biology II
  • Lecture: 3 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: During the semester (summer session)
  • Subject examined: Cancer biology II
  • Lecture: 3 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional

Reference week

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