Advanced bioengineering methods laboratory
BIOENG-444 / 4 credits
Teacher(s): Fantner Georg, Guiducci Carlotta, Radenovic Aleksandra
Language: English
Withdrawal: It is not allowed to withdraw from this subject after the registration deadline.
Remark: The course is held in an amended format giving more freedom to students to learn plan and perform research
Summary
Advanced Bioengineering Methods Laboratories (ABML) offers laboratory practice and data analysis. These active sessions present a variety of techniques employed in the bioengineering field and matching a quantitative and technological based approach.
Content
Keywords
Atomic force microscopy (AFM), Lab on the chip (LOC) , Brownian motion, Optical trapping , Surface Plasmon Resonance. bioanalytics, surface design, writing scientific papers
Learning Prerequisites
Required courses
Required background: Biophysics I, Biothermodynamics, Biomicroscopy I, + mandatory courses of M1
Expected student activities
Beyond the work requested during the supervised sessions (practice and analysis), the student will have to:
- Read the introduction of each topic before the corresponding practice, and summarize this information in his laboratory notebook.
- Review the data analysis tools needed for the analysis sessions and prepare the required calculations ahead of the corresponding analysis session.
- Fill the laboratory notebook progressively along the semester.
- Develop a research plan for the independent project
- Write the research paper
The workload varies widely with the capabilities of each student. However, we expect, for each of the 6 topics investigated, an approximate working time of
- 2 h : Preparation of the practical session
- 4 h : Practical session
Resources
Bibliography
- Handouts given during the course.
- Intermolecular and Surface Forces, J. Israelachvili, Academic press
- Surface Plasmon resonance Based Sensors, J.Homola et al., Springer
- Surface Design: Applications in Bioscience and Nanotechnology, R. Forch, H. Schonherr, A.T. Jenkins, Wiley
- "Introduction to Error Analysis: The Study of Uncertainties in Physical Measurements," Taylor, John R., 1997, University Science Books,
- Optical Trapping Review : K.C. Neuman & S.M. Block, "Optical trapping," Rev. Sci. Instrum. 75 (2003).
- Lab on a Chip Technology, Volume 1: Fabrication and Microfluidics, Keith E. Herold and Avraham Rasooly, Caister Academic Press, 2009
- Atomic Force Microscopy, Peter Eaton and Paul West, Oxford University Press 2010
Ressources en bibliothèque
- Intermolecular and Surface Forces / Israelachvili
- Surface Plasmon resonance Based Sensors / Homola
- Surface Design: Applications in Bioscience and Nanotechnology / Forch
- Introduction to Error Analysis / Taylor
- Optical Trapping Review / Neuman
- Lab on a Chip Technology / Herold
- Atomic force microscopy/ Peter Eaton ; Paul West (http://beast-epfl.hosted.exlibrisgroup.com/primo_library/libweb/action/search.do?cs=frb&ct=frb&frbg=&fctN=facet_frbrgroupid&fctV=104137913&doc=TN_ebi01_prod006075632&lastPag=&lastPagIndx=1&rfnGrp=frbr&dscnt=0&frbg=&scp.scps=scope%3A(EPFL_SFX)%2CPrimo2Primo_41EPFL&tab=default_tab&dstmp=1433946714337&srt=rank&ct=search&mode=Basic&&dum=true&tb=t&indx=1&vl(freeText0)=Paul%20West&vid=EPFL&fn=search#)
Ressources en bibliothèque
- Optical Trapping Review / Neuman
- Surface Plasmon resonance Based Sensors / Homola
- An introduction to Error Analysis / Taylor
- Lab on a Chip Technology / Herold
- Atomic force microscopy/ Peter Eaton ; Paul West
- Intermolecular and Surface Forces / Israelachvili
- Surface Design: Applications in Bioscience and Nanotechnology / Förch
Notes/Handbook
Can be downloaded from
http://lben.epfl.ch/Teaching
Moodle Link
In the programs
- Semester: Spring
- Number of places: 24
- Exam form: During the semester (summer session)
- Subject examined: Advanced bioengineering methods laboratory
- TP: 4 Hour(s) per week x 14 weeks
- Type: optional
- Semester: Spring
- Number of places: 24
- Exam form: During the semester (summer session)
- Subject examined: Advanced bioengineering methods laboratory
- TP: 4 Hour(s) per week x 14 weeks
- Type: optional
- Number of places: 24
- Exam form: During the semester (summer session)
- Subject examined: Advanced bioengineering methods laboratory
- TP: 4 Hour(s) per week x 14 weeks
- Type: mandatory
Reference week
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