Fiches de cours 2017-2018

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Structure and reactivity

CH-432

Enseignant(s) :

Cramer Nicolai

Langue:

English

Summary

To develop a detailed knowledge of the key steps of advanced modern organic synthesis going beyond classical chemistry of olefins and carbonyls.

Content

1. Repetition of the chemistry of olefins and carbonyls
- limitations
2. Rearrangements
- Sigmatropic: Claisen, Ireland-Claisen, Johnson-Claisen, Eschenmoser, Wittig, Evans-Mislow
- Reactive intermediates : cations, carbenes, nitrenes
3. Cyclisations and Cycloadditions
- Pericyclic reactions
- Diels-Alder (normal, hetero, inverse electron demand)
- Dipolar cycloadditions
4. Radical- and Photochemistry
5. Strrategy of Umpolung
- Stoichiometric and catalytic
6. Metal-catalysis in Organic Chemistry
- Cross-coupling and metathesis
- Olefins and C-H bonds functionalization
- Synthesis of carbo- and heterocyclic systems

Learning Outcomes

By the end of the course, the student must be able to:

Transversal skills

Teaching methods

ex cathedra lecture

Assessment methods

final oral exam

Resources

Websites

Dans les plans d'études

Semaine de référence

 LuMaMeJeVe
8-9     
9-10     
10-11     
11-12     
12-13     
13-14     
14-15     
15-16    BSP234
16-17    
17-18     
18-19     
19-20     
20-21     
21-22     
 
      Cours
      Exercice, TP
      Projet, autre

légende

  • Semestre d'automne
  • Session d'hiver
  • Semestre de printemps
  • Session d'été
  • Cours en français
  • Cours en anglais
  • Cours en allemand