Fiches de cours 2018-2019

PDF

Selected topics in life sciences

BIOENG-430

Enseignant(s) :

Lashuel Hilal

Langue:

English

Summary

The course presents an overview on how recent advances at the interfaces of biology, biotechnology, engineering, physical sciences, and medicine are 1) shaping the landscape of biomedical research; 2) contributing to improving our quality of life and; 3) addressing global health challenges today.

Content

The lectures will highlight some of the latest breakthroughs in biology, biotechnology, chemical biology, synthetic biology, genomics, neuroengineering, and genetic engineering and illustrate how they are being applied today to advance our understanding of living systems and to develop novel tools and therapies for early diagnosis and treatment of human diseases.

The impact on the biotechnology and biomedical industry and ethical implication of each technology will also be discussed.

The topics will include, but not limited to, genome sequencing technologies, genetic editing (CRISPR), personalized medicine and personalized genomics, induced pluripotent stem cells and regenerative medicine, organoids, phage display technologies and antibody and protein engineering in drug discovery, vaccines, synthetic biology, nucleic acid based therapies, manufacturing of biologic medicine, the microbiome and the gut-brain axis in health and disease. 

 

Keywords

Biotechnology, life sciences, gene sequencing, genetic engineering, synthetic biology, stem cells, microbiome, CRISPR, antibodies, proteins, regenerative medicine, molecular diagnostics, neuroengineering, personalized and precision medicine.

 

Learning Prerequisites

Required courses

None

Recommended courses

Biology of the Cell, Biochemistry, Biological Chemistry, Organic Chemistry.

 

Important concepts to start the course

General knowledge about 

1) Genome Sequencing

2) The human Genome Project

3) Personalized Medicine

4) Stem Cells and Regenerative Therapy

5) Genetic Engineering

Learning Outcomes

By the end of the course, the student must be able to:

Transversal skills

Teaching methods

The course instructor and/or experts in the relevant topics will give the lectures. Each lecture will be followed by

1) an in class discussion on the ethical implications and economic and societal impact of the specific technology or scientific advances covered in the lecture

2) discussion on latest related discoveries shaping the headlines this fall

or

3) Student presentations on some of the latest scientific discoveries or breakthroughs and team projects. 

 

Expected student activities

In addition to attending the lectures, students are expected to dedicated three weekly hours of personal time to preparing for the lectures and to complete homework assignments.  

 

Assessment methods

Homework assignments (50%) Students will be asked to provide a brief biweekly report (5-6 slides) highlighting one the latest breakthroughs in biotechnology or innovations in the areas mentioned above that were reported on in the scientific and general media during this period.

Semester Team projects (25%): To be decided based on the student number and background

 

Final Exam (25%)

A written exam based on the concepts and materials covered in the lecture notes only.  The students will be informed of which topics/concepts and course material will be covered in the final exam. 

 

Supervision

Office hours Yes
Assistants Yes

Resources

Virtual desktop infrastructure (VDI)

Yes

Bibliography

Chapters from books available at the EPFL Library and selected articles from scientific journals and the general media will be provided to prepare for the lectures and for in class discussions and debates on specific relevant topics.  Additional recommended reading and reference materials will be made available for motivated students.

 

 

Dans les plans d'études

Semaine de référence

 LuMaMeJeVe
8-9     
9-10     
10-11     
11-12     
12-13     
13-14 MED 2 1522   
14-15    
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     
 
      Cours
      Exercice, TP
      Projet, autre

légende

  • Semestre d'automne
  • Session d'hiver
  • Semestre de printemps
  • Session d'été
  • Cours en français
  • Cours en anglais
  • Cours en allemand