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Fiches de cours
Scientific literature analysis in computational molecular biology
BIO-468
Enseignant(s) :
Dal Peraro MatteoLangue:
English
Withdrawal
It is not allowed to withdraw from this subject after the registration deadline.Remarque
MA3 only - only one registration per student to a scientific thinking courseSummary
The goal is to learn to analyze a paper critically, asking whether the data presented support the conclusions that are drawn. The analysis is presented in the form of a summary abstract and critical, constructive referee's report.Content
The goal of the course is to teach you to read a paper critically and understand its content. We will examine published papers and discuss which conclusions can be justified and which require some wishful thinking. We will dissect papers in the field of `Computational Molecular Biology¿, discussing recent development, as well as classics. More specific areas will include `Systems biology approaches for gene expression analysis¿, `Population genetics of adaptation¿, `Molecular modeling¿. Each week, we will ask you to evaluate a paper, and one of the participants will lead the discussion (oral presentation, journal club). Each of you will be expected to produce a summary of the main findings in the proper context, and an assessment of the strengths and weaknesses of the paper. You will present the paper from this standpoint. This will require you to study background material so that your presentation places the paper in context.
The assessment will be based on your oral presentations, written submissions and participation in the discussions throughout the course. There will be an exam in the final week of the course, in which you will have to provide a written assessment of a paper.
Keywords
critical reading, computational biologyLearning Prerequisites
Required courses
None, but a good knowledge of basic biology and bioinformatics is desirable.
Learning Outcomes
By the end of the course, the student must be able to:Transversal skills
- Give feedback (critique) in an appropriate fashion.
- Access and evaluate appropriate sources of information.
- Demonstrate the capacity for critical thinking
- Continue to work through difficulties or initial failure to find optimal solutions.
Teaching methods
Lectures to give background information required to read the paper
Group discussion of paper
Written exam at the end of the course
Expected student activities
Oral presentation of paper, singly or in group.
Read background literature to present the paper in an appropriate context.
Prepare a written abstract of the paper, and a critical, constructive evaluation of the paper.
Assessment methods
In course assessment of the quality of the written abstract and referee's report.
In course assessment of the oral presentation, and participation in discussions.
Written examination in the final week of the course. This is likely to be preparation of an abstract and/or referee's report for a paper that will be provided on the day of the examination. More details will be given during the course.
Supervision
Office hours | Yes |
Forum | No |
Dans les plans d'études
- Bioingénierie, 2018-2019, Master semestre 1
- SemestreAutomne
- Forme de l'examenPendant le semestre
- Crédits
5 - Matière examinée
Scientific literature analysis in computational molecular biology - Nombre de places
12 - Cours
2 Heure(s) hebdo x 14 semaines - Exercices
3 Heure(s) hebdo x 14 semaines
- Semestre
- Bioingénierie, 2018-2019, Master semestre 3
- SemestreAutomne
- Forme de l'examenPendant le semestre
- Crédits
5 - Matière examinée
Scientific literature analysis in computational molecular biology - Nombre de places
12 - Cours
2 Heure(s) hebdo x 14 semaines - Exercices
3 Heure(s) hebdo x 14 semaines
- Semestre
- Ingénierie des sciences du vivant, 2018-2019, Master semestre 1
- SemestreAutomne
- Forme de l'examenPendant le semestre
- Crédits
5 - Matière examinée
Scientific literature analysis in computational molecular biology - Nombre de places
12 - Cours
2 Heure(s) hebdo x 14 semaines - Exercices
3 Heure(s) hebdo x 14 semaines
- Semestre
- Sciences et technologies du vivant - master, 2018-2019, Master semestre 1
- SemestreAutomne
- Forme de l'examenPendant le semestre
- Crédits
5 - Matière examinée
Scientific literature analysis in computational molecular biology - Nombre de places
12 - Cours
2 Heure(s) hebdo x 14 semaines - Exercices
3 Heure(s) hebdo x 14 semaines
- Semestre
- Sciences et technologies du vivant - master, 2018-2019, Master semestre 3
- SemestreAutomne
- Forme de l'examenPendant le semestre
- Crédits
5 - Matière examinée
Scientific literature analysis in computational molecular biology - Nombre de places
12 - Cours
2 Heure(s) hebdo x 14 semaines - Exercices
3 Heure(s) hebdo x 14 semaines
- Semestre
Semaine de référence
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20-21 | |||||
21-22 |
légende
- Semestre d'automne
- Session d'hiver
- Semestre de printemps
- Session d'été
- Cours en français
- Cours en anglais
- Cours en allemand