Frontiers in Chemical Synthesis. Towards Sustainable Chemistry
CH-707 / 2 crédits
Enseignant(s): Hu Xile, Waser Jérôme
Langue: Anglais
Remark: Next time: Spring 2026
Frequency
Every 3 years
Summary
This training will empowered the student with all the tools of modern chemistry, which will be highly useful for his potential career as a process or medicinal chemist in industry.
Content
Following topics will be at the focus of the lecture:
- The concepts of atom and step economy in synthesis
- Recent progresses in metal-catalyzed SP, SP2 and Sp3 C-C and C-X couplings
- The activation and direct functionalization of feedstocks compounds via C-H and C-C Activation
- The development of organocatalysis: towards metal-free catalysis
- Direct functionalization of olefins, including hydroamination, hydrogenation, hydrosilylation, hydroformylation and other C-C bond forming reactions
- The potential of radical chemistry for C-C and C-X bond formation
- Metal-Catalyzed Carbocyclization: From Ru and Rh-mediated cycloadditions to Pt and Au chemistry: the relative effect in organic chemistry.
- One-pot multi-steps reactions: avoiding time and ressource-consuming isolation procedures
- "New" technologies in the organic chemistry laboratory: microwave, ultrason, solid-phase synthesis, organic chemistry in water, parallel synthesis and reactions in flow reactors.
Keywords
Organometallic Chemistry, Organic Chemistry, Catalysis, Synthesis Efficiency, Sustainable Chemistry
Learning Prerequisites
Recommended courses
Master EPFL or Equivalent
Dans les plans d'études
- Nombre de places: 8
- Forme de l'examen: Multiple (session libre)
- Matière examinée: Frontiers in Chemical Synthesis. Towards Sustainable Chemistry
- Cours: 10 Heure(s)
- TP: 36 Heure(s)