Fiches de cours 2017-2018

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Cellular Signalling

CH-411

Enseignant(s) :

Hovius Rudolf

Langue:

English

Summary

Presentation of selected signalling pathways with emphasis on both the mechanism of action of the molecules involved, molecular interactions and the role of their spatio-temporal organization within the cell, considering cellular dimensions and conditions.

Content

Ligand binding and receptor activation.Receptor systems in plasma membrane, cytosol and nucleus. Lipids, proteins and molecular interactions. Regulation of activity and covalent modification. Spatial and temporal organisation of molecules and signalling efficacy.

Keywords

Cellular signalling, molecular interactions, space and time, cellular conditions, receptor, ligand, membranes, protein modifications

Learning Prerequisites

Required courses

Biochemistry I   (CH-111)

Biophysics I & II (CH-311 & 312)

Recommended courses

Biochemistry II (CH 313)

Reaction kinetics

Important concepts to start the course

Biochemistry, cell and organells, membranes, proteins, biophysical methods. physical chemistry

Learning Outcomes

By the end of the course, the student must be able to:

Teaching methods

Lectures & discussion

Expected student activities

Active participation to lectures; read and interpret scientific reviews and papers

Assessment methods

Oral exam, without preparation

Supervision

Others during course or on rendez-vous

Resources

Bibliography

course hand-outs

review and research articles

Notes/Handbook

standard text books

Websites

Dans les plans d'études

Semaine de référence

 LuMaMeJeVe
8-9     
9-10     
10-11     
11-12     
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     
En construction
 
      Cours
      Exercice, TP
      Projet, autre

légende

  • Semestre d'automne
  • Session d'hiver
  • Semestre de printemps
  • Session d'été
  • Cours en français
  • Cours en anglais
  • Cours en allemand