Fiches de cours

Cell and developmental biology for engineers

BIO-221

Enseignant(s) :

Gönczy Pierre
Oates Andrew Charles

Langue:

English

Summary

The students will learn essentials of cell and developmental biology, with an emphasis on animal model systems and quantitative approaches.

Content

The students will be introduced to fundamental concepts and questions in cell and developmental biology, with an emphasis on animal model systems and quantitative approaches to analyze them. Topics that will be covered include fertilization, cell polarity, genome activation, patterning, axis specification, differentiation, gastrulation, scaling, organogenesis, size control, regeneration, cell death, germ cell specification, cell migration, multicellularity and evolution. Students will learn that developmental systems must have the correct constituents (the what question), positional information (the where question), temporal information (the when question), as well as appropriate relationships between genes, cells, tissues and organisms (the how questions). Parallels will be drawn between various concepts familiar to engineers and developmental systems to highlight underlying guiding principles. 

Keywords

Cell biology, developmental biology, quantitative aspects, embryogenesis, model systems (C. elegans, Drosophila, zebrafish, mouse, ...), research strategies, experimental approaches, mathematical modeling, computer simulations.

Learning Prerequisites

Required courses

Second year Life Sciences BSc, but motivated and equally prepared students from other disciplines are welcome to join.  

Learning Outcomes

By the end of the course, the student must be able to:

Transversal skills

Teaching methods

Each week, typically the first two hours will consist of lectures given by the teachers, whereas the next two hours will consist of reading, demonstrations and/or exercises, including computer simulations (depending on the week).

Expected student activities

The students are expected to participate actively in all four hours of class. Moreover, four hours of personal study per week are expected on average.

Assessment methods

Two continuous evaluations will be performed during the semester (in week 7 and week 14); details of the exam format will be provided in due time.

Supervision

Office hours No
Assistants Yes
Forum No
Others Appointments with the teachers by e-mail.

Resources

Bibliography

Some of the illustrations will be drawn from:

Developmental Biology, Gilbert and Barresi, 11th edition, Sinauer, Oxford

Other sources will be indicated on the lecture slides.

Notes/Handbook

The lectures slides will also be made available through Moodle.

Dans les plans d'études

Semaine de référence

 LuMaMeJeVe
8-9     
9-10     
10-11CE5  CM013
MAB1486
 
11-12   
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     
 
      Cours
      Exercice, TP
      Projet, autre

légende

  • Semestre d'automne
  • Session d'hiver
  • Semestre de printemps
  • Session d'été
  • Cours en français
  • Cours en anglais
  • Cours en allemand