Coursebooks 2017-2018

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Total synthesis of natural products

CH-438

Lecturer(s) :

Zhu Jieping

Language:

English

Summary

Complex polycyclic natural products are chosen to illustrate the evolution of the state-of-the-art of the field, the interplay between strategy and new reactions as well as the importance of implementing multi-bond forming processes in a synthesis.

Content

Retro-synthesis and synthesis of different classes of natural products important for their structure and/or bioactivity.

Keywords

Retro-synthetic analysis, Synergism between strategy and new reactions, Domino reactions, multicomponent reactions, Oxidative coupling, Pattern Recognition, Hidden Symmetry, C-H Functionalization, Asymmetric organocatalysis

 

Learning Prerequisites

Recommended courses

General knowledge of organic reactions. Basic knowledge of retro-syntheis. EPFL lectures fonctions et réactions organiques I and II, synthèse asymétrique, target synthesis, structure and reactivity or equivalent courses.

Learning Outcomes

By the end of the course, the student must be able to:

Supervision

Office hours Yes
Assistants Yes
Forum Yes

Resources

Ressources en bibliothèque
Websites

In the programs

Reference week

 MoTuWeThFr
8-9     
9-10     
10-11  CHB331  
11-12    
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     
 
      Lecture
      Exercise, TP
      Project, other

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  • Autumn semester
  • Winter sessions
  • Spring semester
  • Summer sessions
  • Lecture in French
  • Lecture in English
  • Lecture in German