Coursebooks 2016-2017

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Principles and applications of systems biology

ChE-411

Lecturer(s) :

Hatzimanikatis Vassily

Language:

English

Summary

The course introduces key concepts from systems biology and systems engineering methodologies used for the study of complex biological networks. It presents and analyzes the methodologies for the development of models of biological networks.

Content

The course will include the following topics:

 

Learning Prerequisites

Recommended courses

Analysis I-III, linear algebra, probability and statistics, physical chemistry.

The building of working groups will make it possible for people with partial knowledge in these fields to contribute depending on their formation.

For SSV students: Dynamical Systems Theory for Engineers or "Mathematical and Computational Models in Biology" course, Felix Naef

Important concepts to start the course

For the computational exercises, MATLAB® will be used intensively.

Learning Outcomes

By the end of the course, the student must be able to:

Transversal skills

Teaching methods

Teaching in classroom, paper reviews, project.

Expected student activities

Presentations and critical analysis of papers.

Project.

Assessment methods

- Presentations of papers from the literature (30%)

- Mid-semester and final project presentation (70%)

Supervision

Office hours Yes
Assistants Yes

Resources

Bibliography

Foundations of System Biology, Edited by Hiraoki Kitano. MIT Press 2001

Systems Biology, By Edda Klipp et al. Wiley-Blackwell 2009.

An Introduction to Systems Biology: Design Principles of Biological Circuits, by Uri Alon. Chapman and Hall/CRC 2006.

Computational Modeling of Genetic and Biochemical Networks, by James M. Bower and Hamid Bolouri. Bradford 2004.

Modeling Differential Equations in Biology, by Clifford H. Taubes. Prentice Hall 2000.

Ressources en bibliothèque
Websites

In the programs

Reference week

 MoTuWeThFr
8-9     
9-10     
10-11     
11-12     
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     
Under construction
 
      Lecture
      Exercise, TP
      Project, other

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  • Autumn semester
  • Winter sessions
  • Spring semester
  • Summer sessions
  • Lecture in French
  • Lecture in English
  • Lecture in German