Coursebooks

Neuronal circuits underlying goal-directed behavior

BIO-697

Lecturer(s) :

Petersen Carl

Language:

English

Frequency

Only this year

Remarque

Next time: Spring 2018

Summary

The brain can be viewed as a network of neurons receiving sensory input and carrying out experience- and context-dependent computations through complex synaptic interactions to drive motor output, i.e. behavior. Here, we will study recent advances in knowledge of neural circuits in the mouse brain.

Content

Students will learn state-of-the-art analyses of neuronal circuit function contributing to simple learned goal-directed behaviors in mice. We will critically evaluate current understanding through in depth discussion of various topics, guided by selected papers (Thursdays 5 - 7 pm; 7 x 2 hours = 1 ECTS):

22nd March 2018

Guo ZV, Li N, Huber D, Ophir E, Gutnisky D, Ting JT, Feng G, Svoboda K (2014) Flow of cortical activity underlying a tactile decision in mice. Neuron 81:179-194. 

29th March 2018

Pinto L, Dan Y (2015) Cell-type-specific activity in prefrontal cortex during goal-directed behavior. Neuron 87:437-450.

12th April 2018

Kuchibhotla KV, Gill JV, Lindsay GW, Papadoyannis ES, Field RE, Sten TAH, Miller KD, Froemke RC (2016) Parallel processing by cortical inhibition enables context-dependent behavior. Nature Neuroscience 20: 62-71.

19th April 2018

Guo W, Clause AR, Barth-Maron A, Polley DB (2017) A corticothalamic circuit for dynamic switching between feature detection and discrimination. Neuron 95: 180-194.

26th April 2018

Leinweber M, Ward DR, Sobczak JM, Attinger A, Keller GB (2017) A sensorimotor circuit in mouse cortex for visual flow predictions. Neuron 95: 1420-1432.

17th May 2018

Driscoll LN, Pettit NL, Minderer M, Chettih SN, Harvey CD (2017) Dynamic reorganization of neuronal activity patterns in parietal cortex. Cell 170: 986-999.

28th June 2018

Aronov D, Nevers R, Tank DW (2017) Mapping of a non-spatial dimension by the hippocampal-entorhinal circuit. Nature 543: 719-722.

13th July 2018 (written report submission deadline)

For written evaluation, each student will critically discuss a neuronal circuit for a specific mouse behavior.

Note

Maximun number - 8 students

Keywords

Neuronal circuits

Mouse behavior

Learning Prerequisites

Important concepts to start the course

Strong interest in Neuronal Circuit function

Learning outcome - to critically evaluate studies of neural circuits and behavior.

Assessment methods

13th July 2018 (written report submission deadline)

For written evaluation, each student will critically discuss a neuronal circuit for a specific mouse behavior.

In the programs

    • Semester
    • Exam form
       Written
    • Credits
      1
    • Subject examined
      Neuronal circuits underlying goal-directed behavior
    • Lecture
      14 Hour(s)
    • Exercises
      14 Hour(s)

Reference week

 
      Lecture
      Exercise, TP
      Project, other

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  • Autumn semester
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  • Spring semester
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  • Lecture in French
  • Lecture in English
  • Lecture in German