BIOENG-399 / 4 credits

Teacher: Tang Li

Language: English


Summary

Immunoengineering is an emerging field where engineering principles are grounded in immunology. This course provides students a broad overview of how engineering approaches can be utilized to study immunology, model immune systems, modulate immune response, and develop novel immunotherapies.

Content

 

Part 1. Understanding immunology with engineering tools

Introduction of the course and expectation

Overview of the fundamentals of immunology

Definition and scope of immunoengineering

Engineering tools and new technologies to understand immunology

 

Part 2. Engineering novel immunotherapies for diseases

Cancer and cancer immunotherapies

Concept and overview of drug delivery

Materials engineering in the advancement of immunotherapies

Immune cell engineering and genetic engineering

Metabolic engineering and immune modulation

Overview of adaptive immunity and vaccines

Design of immunogenic vaccines

Other vaccines

Protein engineering in vaccine design

 

Part 3. Applications and practical issues

Considerations on immune drug discovery and development

Keywords

 

immunology, immunoengineering, vaccines, infectious diseases, autoimmunity, cancer, materials engineering, drug delivery, protein engineering, drug discovery and development

Learning Prerequisites

Required courses

This class requires a basic knowledge in biology, physics, chemistry, and materials science.

BIO-310 Immunology or an equivalent is required

Learning Outcomes

By the end of the course, the student must be able to:

  • Describe the concept of immunoengineering
  • Make examples of how engineering approaches has led to advancements in immunotherapy
  • Take into consideration how to apply engineering principles to immunology research and applications
  • Specify 1. Understand how to apply engineering principles to immunology research and applications
  • 2. Show examples of how engineering approaches has led to advancements in immunotherapy and diagnosis
  • 3. Describe the discovery or development of new immunotherapies from recent scientific literatures

Transversal skills

  • Write a scientific or technical report.
  • Communicate effectively, being understood, including across different languages and cultures.
  • Write a scientific or technical report.
  • Communicate effectively with professionals from other disciplines.

Assessment methods

Scientific ssay writing: 30%

Final written exam: 70%

 

Supervision

Office hours Yes
Assistants Yes
Forum Yes
Others

Resources

Bibliography

Library resources (good to read, but not required)

How the immune system works: Lauren Sompayrac. all versions

Kuby Immunology: Owen, Pung, Stranford. all versions

Cellular and Molecular Immunology: Abbas & Lichtman. all versions

Janeway's immunobiology: Kenneth Murphy ; Charles A. Janeway ; Allan Mowat

all versions

 

Ressources en bibliothèque

Notes/Handbook

Slides/Notes will be provided on Moodle webpageq

Moodle Link

In the programs

  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Immunoengineering
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Immunoengineering
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Immunoengineering
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Immunoengineering
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Immunoengineering
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Spring
  • Exam form: Written (summer session)
  • Subject examined: Immunoengineering
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional
  • Exam form: Written (summer session)
  • Subject examined: Immunoengineering
  • Courses: 2 Hour(s) per week x 14 weeks
  • Exercises: 2 Hour(s) per week x 14 weeks
  • Type: optional

Reference week

Friday, 8h - 10h: Lecture CE1106

Friday, 10h - 12h: Exercise, TP CE1106

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