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Coursebooks
Chemical biology
CH-412
Lecturer(s) :
Aye YimonFerreira De Sousa Correia Bruno Emanuel
Heinis Christian
Hovius Rudolf
Language:
English
Summary
The class will discuss how the tools of chemistry can be utilized to address important problems in biology. Through the discussion of landmark papers in chemical biology the students will be introduced into research at the interface of chemistry and biology.Content
The class will discuss how the tools of chemistry can be utilized to address important problems in biology. Through the discussion of landmark papers in chemical biology the students will be introduced into research at the interface of chemistry and biology.
Keywords
chemical biology, protein chemistry, chemical probes, protein engineering, chemical genetics
Learning Outcomes
By the end of the course, the student must be able to:- Characterize the main concepts in chemical biology
- Design an experiment to engineer an autofluorescent protein
- Describe how proteins can be chemically modified in live cells
- Develop an experiment to exploit unnatural amino acids
- Describe a strategy to generate allele-specific kinase inhibitors
- Categorize different strategies to derivatize proteins for mechanistic studies
- Contrast forward and reverse chemical genetics
- Develop a strategy for determining the protein target of a bioactive molecule
Transversal skills
- Access and evaluate appropriate sources of information.
Teaching methods
Ex cathedera and discussions
Expected student activities
Read papers to be discussed before the class
Assessment methods
100% Oral exam
Supervision
Office hours | No |
Assistants | No |
Forum | No |
Others | Students are welcomed to contact Kai Johnsson via email or after the class to schedule appointments |
Resources
Ressources en bibliothèque
Notes/Handbook
Papers and slides will be distributed via the the website of the teaching section or by email before the class.
Websites
In the programs
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- Molecular & Biological Chemistry, 2018-2019, Master semester 2
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- Life Sciences Engineering, 2018-2019, Master semester 2
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- Life Sciences and Technologies - master program, 2018-2019, Master semester 2
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- Semester
- Neuroscience (edoc), 2018-2019
- SemesterSpring
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- Semester
Reference week
Mo | Tu | We | Th | Fr | |
---|---|---|---|---|---|
8-9 | |||||
9-10 | |||||
10-11 | |||||
11-12 | |||||
12-13 | |||||
13-14 | CE1105 | ||||
14-15 | |||||
15-16 | |||||
16-17 | |||||
17-18 | |||||
18-19 | |||||
19-20 | |||||
20-21 | |||||
21-22 |
Lecture
Exercise, TP
Project, other
legend
- Autumn semester
- Winter sessions
- Spring semester
- Summer sessions
- Lecture in French
- Lecture in English
- Lecture in German