Coursebooks 2017-2018

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Cellular Signalling

CH-411

Lecturer(s) :

Hovius Rudolf

Language:

English

Summary

Presentation of selected signalling pathways with emphasis on both the mechanism of action of the molecules involved, molecular interactions and the role of their spatio-temporal organization within the cell, considering cellular dimensions and conditions.

Content

Ligand binding and receptor activation.Receptor systems in plasma membrane, cytosol and nucleus. Lipids, proteins and molecular interactions. Regulation of activity and covalent modification. Spatial and temporal organisation of molecules and signalling efficacy.

Keywords

Cellular signalling, molecular interactions, space and time, cellular conditions, receptor, ligand, membranes, protein modifications

Learning Prerequisites

Required courses

Biochemistry I   (CH-111)

Biophysics I & II (CH-311 & 312)

Recommended courses

Biochemistry II (CH 313)

Reaction kinetics

Important concepts to start the course

Biochemistry, cell and organells, membranes, proteins, biophysical methods. physical chemistry

Learning Outcomes

By the end of the course, the student must be able to:

Teaching methods

Lectures & discussion

Expected student activities

Active participation to lectures; read and interpret scientific reviews and papers

Assessment methods

Oral exam, without preparation

Supervision

Others during course or on rendez-vous

Resources

Bibliography

course hand-outs

review and research articles

Notes/Handbook

standard text books

Websites

In the programs

Reference week

 MoTuWeThFr
8-9     
9-10     
10-11     
11-12     
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     
Under construction
 
      Lecture
      Exercise, TP
      Project, other

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  • Autumn semester
  • Winter sessions
  • Spring semester
  • Summer sessions
  • Lecture in French
  • Lecture in English
  • Lecture in German