Biomaterials (pour MX)

MSE-471 / 4 credits

Teacher: Bastings Maartje Martina Cornelia

Language: English

Withdrawal: It is not allowed to withdraw from this subject after the registration deadline.

Summary

The course introduces the main classes of biomaterials used in the biomedical field. The interactions with biological environment are discussed and challenges highlighted. State of the art examples per type of material are discussed. Students will engineer a biomaterial & study cell compatibility.

Content

BLOCK 1:

Lecture 1.    Intro to biomaterials

Lecture 2.    Naturally derived vs Manmade biomaterials

Lecture 3.    Surfaces vs bulk

Lecture 4.    Polymers and nanoparticles

Exercise session 1

 

BLOCK 2:

Lecture 5.    Materials for drug delivery

Lecture 6.    Materials for cell adhesion and tissue engineeing

Lecture 7.    Materials for immune engineering

Exercise session 2

 

BLOCK 3:

Lecture 8.  Characterization and performance of biomaterials

Lecture 9.  Translation to industry, patents and spin-offs

Lecture 10.  Regulatory aspects and trials

 

Lecture 11.  Revision and conclusion

 

Keywords

Biomaterials, biocompatibility, biofunctionality, implants, nanotechnology, tissue engineering, drug-delivery, nanoparticles. 

Learning Prerequisites

Required courses

Introduction to materials science

Biology for engineers

Recommended courses

Materials, metallurgy, polymer, ceramics, soft matter

Learning Outcomes

By the end of the course, the student must be able to:

  • Estimate a biomaterial in function of the application
  • Compare developments of new biomaterials
  • Describe the interactions with biological environment
  • Describe the translation of a biomaterial to commercial use
  • Design a nanoparticle for targeting/drug delivery
  • Compare biocompatibility of various materials
  • Describe requirements to limit toxicity

Transversal skills

  • Communicate effectively with professionals from other disciplines.
  • Respect relevant legal guidelines and ethical codes for the profession.
  • Collect data.
  • Access and evaluate appropriate sources of information.

Teaching methods

Ex cathedra and invited speakers

Practicum at DLL laboratories: development and characterization of a soft biomaterial as scaffold for cell proliferation.

Expected student activities

Attendance at lectures.

Presence at DLL sessions.

Assessment methods

Written exam in exam period (75%)

Laboratory paper (25%, hand in at last scheduled MSE471 course day of semester)

 

Supervision

Office hours Yes
Assistants Yes
Forum No

Resources

Ressources en bibliothèque

Notes/Handbook

All necessary documentation will be made available in the Moodle of this course

Moodle Link

Videos

In the programs

  • Semester: Fall
  • Number of places: 32
  • Exam form: Written (winter session)
  • Subject examined: Biomaterials (pour MX)
  • Courses: 2 Hour(s) per week x 14 weeks
  • TP: 2 Hour(s) per week x 14 weeks
  • Type: optional
  • Semester: Fall
  • Number of places: 32
  • Exam form: Written (winter session)
  • Subject examined: Biomaterials (pour MX)
  • Courses: 2 Hour(s) per week x 14 weeks
  • TP: 2 Hour(s) per week x 14 weeks
  • Type: optional

Reference week

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