Coursebooks 2017-2018

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Advanced principles and applications of systems biology

ChE-421

Lecturer(s) :

Hatzimanikatis Vassily
Miskovic Ljubisa

Language:

English

Summary

This course is a natural continuation of Principles and Applications of System Biology (ChE-411). The goal of this course is to introduce to students systems engineering methodologies as a tool for the study of complex biological networks.

Content

Specific topics include:

mathematical and computational analysis of metabolic reaction networks with focus on dynamic behavior of (bio)chemicalreaction networks including feedback analysis, multi-stability and higher-level circuit properties such as robustness and retroactivity; Network motifs; Probabilistic approach to analysis of biological networks and Bayesian networks.

Systems of study:

metabolic pathways, signaling networks, genetic regulatory networks.

 

Learning Prerequisites

Recommended courses

ChE-411 Principles and Applications of Systems Biology

Important concepts to start the course

For the computational exercises, MATLAB® will be used intensively.

Learning Outcomes

By the end of the course, the student must be able to:

Transversal skills

Assessment methods

Continuous control exam

Resources

Bibliography

An Introduction to Systems Biology: Design Principles of Biological Circuits by Uri Alon

Systems Biology in Practice: Concepts, Implementation and Application by Klipp et al.

Ressources en bibliothèque

In the programs

    • Semester
       Spring
    • Exam form
       During the semester
    • Credits
      3
    • Subject examined
      Advanced principles and applications of systems biology
    • Lecture
      2 Hour(s) per week x 14 weeks
    • Project
      2 Hour(s) per week x 14 weeks

Reference week

 MoTuWeThFr
8-9     
9-10     
10-11     
11-12     
12-13     
13-14     
14-15     
15-16     
16-17     
17-18     
18-19     
19-20     
20-21     
21-22     
Under construction
 
      Lecture
      Exercise, TP
      Project, other

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  • Autumn semester
  • Winter sessions
  • Spring semester
  • Summer sessions
  • Lecture in French
  • Lecture in English
  • Lecture in German