Coursebooks 2017-2018

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Advanced principles and applications of systems biology

ChE-421

Lecturer(s) :

Hatzimanikatis Vassily
Miskovic Ljubisa

Language:

English

Summary

This course is a natural continuation of Principles and Applications of System Biology (ChE-411). The goal of this course is to introduce to students systems engineering methodologies as a tool for the study of complex biological networks.

Content

Specific topics include:

mathematical and computational analysis of metabolic reaction networks with focus on dynamic behavior of (bio)chemicalreaction networks including feedback analysis, multi-stability and higher-level circuit properties such as robustness and retroactivity; Network motifs; Probabilistic approach to analysis of biological networks and Bayesian networks.

Systems of study:

metabolic pathways, signaling networks, genetic regulatory networks.

Learning Prerequisites

Recommended courses

ChE-411 Principles and Applications of Systems Biology

Important concepts to start the course

For the computational exercises, MATLAB® will be used intensively.

Learning Outcomes

By the end of the course, the student must be able to:

Transversal skills

Assessment methods

Continuous control exam

Resources

Bibliography

An Introduction to Systems Biology: Design Principles of Biological Circuits by Uri Alon

Systems Biology in Practice: Concepts, Implementation and Application by Klipp et al.

Ressources en bibliothèque

In the programs

  • Biotechnology minor, 2017-2018, Spring semester
    • Semester
      Spring
    • Exam form
      During the semester
    • Credits
      3
    • Subject examined
      Advanced principles and applications of systems biology
    • Lecture
      2 Hour(s) per week x 14 weeks
    • Project
      2 Hour(s) per week x 14 weeks

Reference week

MoTuWeThFr
8-9
9-10
10-11
11-12
12-13
13-14
14-15
15-16
16-17
17-18
18-19
19-20
20-21
21-22
Under construction
Lecture
Exercise, TP
Project, other

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  • Autumn semester
  • Winter sessions
  • Spring semester
  • Summer sessions
  • Lecture in French
  • Lecture in English
  • Lecture in German